Uncovering The Pharmacological Mechanisms Of Gexia-Zhuyu Formula (Gxzy) In Treating Liver Cirrhosis By An Integrative Pharmacology Strategy
Ge Xia Zhu Yu Tang alleviates blood stasis causing accumulations under the diaphragm by stimulating the blood, dispersing blood stasis, and supporting the flow of qi. This product is only available for sale to healthcare practitioners and TCM students. The Liver is a so-called "Zang" Organ. Sanctions Policy - Our House Rules. The filtering of retrieval results is with a threshold value of p < 0. Until a product has been successfully registered, it will be unavailable for sale in Canada.
Ge Xia Zhu Yu Tang Clan
Plum Flower Brand 膈下逐瘀丸, Drive Out Blood Stasis Below the Diaphragm Pills, Ge Xia Zhu Yu Tang. Ge xia zhu yu tang powder. Chronic pelvic inflammatory disease. T000200576, Anhui, China; 6g), Paeoniae Radix Rudra (Chishao in Chinese, No. Ge Xia Zhu Yu Wan is a candidate for consideration when needing to influence blood stagnation, liver blood stagnation and/or liver qi stagnation. Subsequently, the potential action mechanisms of GXZY on LC predicted by the network pharmacology analyses were experimentally validated in LC rats and LX2 cells.
Statistical Analysis. LAC Local Average Connectivity. Total RNAs were extracted using the RaPure Total RNA Mini Kit (Magen, CN) according to the manufacturer's instructions. In general Mu Dan Pi's main actions are as follows: "Cools the Blood, activates Blood circulation and resolves Blood stasis. Ge Xia Zhu Yu Tang › Veterinarian Recommended Holistic Pet Products. Pharmaceutical Name: Alternate Name: Tangkuei & Corydalis Combination. Xiong and Yan Hu Suo treat both the qi and the blood at the same time and both.
Ge Xia Zhu Yu Wan
We treated LX2 cells with GXZY and detected the cell proliferation viability and migration activity. Japanese Name: Unit Size: 100 gm. The reverse transcription of total RNA to cDNA was performed with qPCR RT Master Mix kit (TOYOBO, JAN). Consult with a physician before use if you have a serious medical condition or use prescription medications. Chen et al., 2020), Moutan Cortex (the dried bark of Paeonia suffruticosa Andr. ) The rats were modeled by intraperitoneal injection of 50% CCl4 and olive oil mixture at 1 ml/kg twice per week for 12 weeks to construct the cirrhosis model. Wu Ling Zhi 6 g, - Dang Gui 9 g, - Chuan Xiong 6 g, - Tao Ren 9 g, - Dan Pi 6 g, - Chi Shao 6 g, - Wu Yao 6 g, - Xuan Hu Suo 3 g, - Gan Cao 9 g, - Xiang Fu 4. Invented in 1830 AD, it belongs to the category of formulas that invigorate Blood and dispel Blood Stagnation. Previous network pharmacological studies had also found that AR and MYC could play a key role in the process of viral hepatitis, liver cirrhosis, and liver cancer (Huang et al., 2012) and inhibit the expression of AR (Kur et al., 2020), JUN (Vogt, 2001), and MYC (Wu et al., 2020), which reduce the occurrence of liver cancer. Bruising, sprains, swelling from soft tissue injuries. Moreover, in the present study, GXZY is also used in treating clinical chronic liver diseases such as liver fibrosis and cirrhosis, and it is reported that GXZY exhibited an excellent anti-liver fibrosis effect in treating chronic hepatitis B (CHB) (Hui, 2016) (Ma, 2015). Uncovering the Pharmacological Mechanisms of Gexia-Zhuyu Formula (GXZY) in Treating Liver Cirrhosis by an Integrative Pharmacology Strategy. REGISTERED CUSTOMERS.
A range of liver issues including hepatitis and cirrhosis. Angelicae Sinensis, Rz. A single formula, alone, may not be sufficient to fully address a particular TCM diagnostic pattern. Possible choppy, deep, slow, bowstring, bound, regularly intermittent, skipping, or absent pulse. Daina, A., Michielin, O., and Zoete, V. (2019). Dimethyl Fumarate Targets GAPDH and Aerobic Glycolysis to Modulate Immunity. Hoehes33342 counterstained the nucleus, and the fluorescence was blue. Removes blood stasis. Avoid using in pregnancy. GXZY might be beneficial to the growth of body weight and slow down liver injury in cirrhotic rats. Volume 13 - 2022 | Uncovering the Pharmacological Mechanisms of Gexia-Zhuyu Formula (GXZY) in Treating Liver Cirrhosis by an Integrative Pharmacology Strategy. Lin, H. Q., Gong, A. G., Wang, H. Y., Duan, R., Dong, T. T., Zhao, K. J., et al. Based on traditional Chinese medical science, TCM systematically prevents and treats complex liver diseases, which has a broad prospect (Song et al., 2018; Li et al., 2020). BC Betweenness Connectivity.
Ge Xia Zhu Yu Tang Powder
Phytomedicine 62, 152930. We used GXZY to treat cirrhotic rats for 1 month, and the degree of fibrous hyperplasia, inflammation, and necrosis in the liver of GXZY group was reduced (Figure 5B). The protein expression levels of Mmp9 in rat. For a range of stagnation issues in the stomach/epigastric/heart region - gastritis, epigastric pain, peptic ulcer disease.
The representative images of HE staining shows the injury changes of the hepatic portal area, hepatic cord, and central vein at eighth week and 12th week. Ingredients: Angelica sinensis root, Prunus persica seed, Carthamus tinctorius flower, Lindera aggregata root, Ligusticum chuanxiong rhizome, Paeonia suffruticosa root-bark, Paeonia lactiflora root, Cyperus rotundus rhizome (vinegar-fried), Citrus aurantium fruit, Boswellia carterii resin (vinegar-fried), Commiphora myrrha resin (vinegar-fried), Corydalis yanhusuo rhizome, Glycyrrhiza uralensis root. Anti-cirrhosis treatment for fibrous tissue hyperplasia and degradation is vital, and it is an important treatment for chronic liver disease. Use with caution in those with qi and blood deficiency. A Novel Chemometric Method for the Prediction of Human Oral Bioavailability. After 48 h, images of the scratches were acquired with a digital camera. Song, Y. N., Chen, J., Cai, F. F., Lu, Y. Y., Chen, Q. L., Zhang, Y.
Formulas & Strategies. Dang Gui (Radix Angelicae Sinensis), 12. Other sets by this creator. If you create a custom formula based on the ingredient, they can be easily included. The Gene Ontology Consortium.