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400 (reference range, 140–280). A. Rituximab cyclophosphamide, vincristine, and prednisone (R-CVP). 9×109/L, and platelet count 398×109/L. D. Involvement of the marrow and distant nodes occurs in about 50% of cases. Peripheral blood smear and bone marrow bx. No cryoglobulins or cold agglutinins were detected.

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Mutational analysis of the marrow aspirate revealed a MYD88 L256P mutation and a CXCR4 mutation. Eight years earlier, she had bilateral breast implants for cosmetic purposes, and no problems had occurred since they were inserted until this time. In general, apart from the marrow morphology, which of the following features strongly suggests a diagnosis of WM rather than IgM myeloma? Hematology case studies with answers pdf book. CLPD-NK must be distinguished from the very aggressive acute NK cell leukemia (ANKL). B. t(11;18), BIRC3–MALT1 fusion. Follicular Lymphoma Case 3. A 45 y/o man presents with excess bleeding/ bruising, an active infection, dizziness and fatigue. The staging investigations confirm Ann Arbor stage I.

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9 °C, his pulse rate was 104 beats/min, and his blood pressure was 100/60 mm Hg. His oral medications included bisoprolol 10 mg/d, perindopril 2. He feels well without fevers, night sweats, weight loss, or pruritus. What treatment do you prescribe? Hematology Case Studies (made up) Flashcards. He was otherwise completely well. What therapies would generally be considered to be inappropriate? The patient was treated with a combination of gemcitabine, L-asparaginase, and oxaliplatin and local radiotherapy. The diagnosis of amyloid is easily missed or delayed, and a high index of suspicion is necessary. Neutropenia in a Patient with Rheumatoid Arthritis. Their CBC reveals low Hg, Hct, and RBCs, and a high reticulocyte count.

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C. CD5+, CD23+, and CD10-. On physical examination, he had conjunctival pallor, normal heart and lung findings, no lymphadenopathy, no hepatomegaly or splenomegaly, and no petechiae or ecchymoses. Excisional biopsy of an axillary node was positive for diffuse, large B-cell lymphoma. Hematology case studies with answers pdf file. Her physical examination revealed a 7- × 3-cm mass in the left lobe of the thyroid. What is the most common type of lymphoma affecting the breast in women without an implant?

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Results of the fecal occult blood test are positive. Similar considerations apply to the use of allografts. His alcohol intake was moderate. AML is the most common acute leukemia in adults. C. t(2;8), IGK–MYC fusion. The disease remains in complete remission. D. 11q copy gain/loss. Hematology and Hemostasis Customer Case Studies and White Papers. Diagnosis: Increase in myeloblasts consistent with AML, nonAPL type. Phototherapy with narrow-band ultraviolet B (NBUVB), topical meclorethamine, and topical glucocorticoids are all skin-directed therapies that could be used first line in this patient. The complete blood cell count and serum creatinine levels are normal. On examination, she is slightly pale with slow cognition and point tenderness over the lumbar spine.

There is no indication for a bone marrow biopsy since the reticulocyte response is appropriate and no other cytopenias are apparent. When she's not busy being a mad scientist, she can be found outside riding her bicycle.

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